In official Phase 3 trial results from March 2026, the most common side effects remain gastrointestinal (nausea, vomiting), with no widespread clinical signal for major psychiatric shifts
With this authorization, we are preparing to test, for the first time in humans, whether a one-time, pancreas-targeted gene therapy delivered via a routine endoscopic procedure could provide durable metabolic control by enabling physiologic, nutrient-responsive GLP-1 expression at the source of disease, said Jacques Bergman, MD, PhD, professor of gastrointestinal endoscopy and deputy chair of the department of gastroenterology and hepatology at Amsterdam UMC, and a principal investigator of the upcoming clinical trial
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Product Benefits GLP-1 supports research into obesity, type 2 diabetes, and cardiovascular health by mimicking GLP-1 activity